Abstract: A new-style vibration isolator composed of wire rope isolators and dishing springs was proposed to reconstruct an explosive laboratory's base-isolated system. The relevant base-isolating projects were presented and the assembled isolators were tested. he dynamic responses of the isolated system were nonlinearly analyzed by two-freedom model with damp. The influence of both stiffness and damp of the isolated layer on the dynamical reaction of isolated system was studied. Some parameters of the isolation system were optimized. When the isolating layer's stiffness is about 10 kN/mm and the ratio of damper is 0.20~0.35, results show that the dynamic loads in the isolating layers are the minimum and the other dynamic reactions of the isolating system satisfy the design needs. The anti-shock capability of the reconstructed laboratory increases 50%.