Abstract: The warhead of conventional weapons is usually composed of a cylindrical charge and a metal case, in which the metal case can affect the attenuation law of peak stress induced by explosion. Therefore, it is important for the blast-resistant design to clarify the attenuation law of stress waves in CF120 concrete induced by cylindrical cased charge explosion. Based on the Kong-Fang concrete material model and the Multi-material Arbitrary Lagrangian Eulerian (MM-ALE) algorithm available in the LS-DYNA, the attenuation law of stress waves in concrete subjected to cylindrical cased charge explosion was numerically investigated in this paper. Firstly, the numerical algorithm and material model parameters were validated against two sets of cylindrical charge explosion tests. Then a series of fully enclosed and partially buried cylindrical charge explosion numerical models were established, in which different aspect ratios, shell thicknesses, and charge buried depths were considered as to analyze the influence of charge shape and shell thickness on stress waves in concrete. Finally, an empirical formula for peak stress of compression wave in concrete induced by cylindrical cased charge explosion was presented based on curve-fitting the numerical data. Numerical results demonstrated that the larger the aspect ratio, the higher the peak stress in the near region, while the opposite law holds for the far region. Besides, increasing the shell thickness will make the peak stress higher, but there is a threshold. The influence of charge shape, shell thickness, and charge buried depth on the peak stress can be quantified by defining the length-diameter ratio, thickness-diameter ratio, and coupling factor of peak stress. The empirical formula for peak stress of compression wave in concrete was demonstrated valid for varied aspect ratio, shell thickness, and charge buried depth, which can provide a reliable reference for blast-resistant design to estimate the peak stress induced by cylindrical cased charge explosion.