Concrete filled double-skin steel tubular (CFDST) members are always employed as load-bearing members in the ultra-high power transmission tower and offshore platform. The impact resistance of this type of members should be considered in the design phase. Therefore, based on the previous test results, totally 200 finite element (FE) models considering the coupling of axial and impact loads were established by ABAQUS software, and the mechanism of impact resistance was analyzed. Influences of nominal steel ratio, hollow ratio, cross-sectional diameter and material strength on the impact resistance of the members were investigated when the axial load ratio ranged from 0 to 0.7. Finally, the calculation formula for the impact bearing capacity was proposed and the dynamic response at the mid-span was predicted on the basis of the methods of dynamic increase factor (DIF) and equivalent single degree of freedom (ESDOF). Results indicated that the impact resistance of circular CFDST columns decreased with the increasing of axial load ratio. Under later impact, CFDST members with hollow ratio lower than 0.7 mainly show flexural failure. The interaction between external steel tube and inner concrete is stronger than that occurs between inner steel tube and concrete. In addition, the nominal steel ratio, outer diameter of the cross-section, yield strength of outer tube, impact velocity and impact mass present significant effects on the peak deflection at the mid-span and the plateau impact force when the axial load ratios range from 0 to 0.7. Effects of hollow ratio and concrete strength are marginal. The proposed calculation methods can reasonably predict the impact bearing capacity and mid-span displacement response of CFDST members when subjected to an impact.