Abstract: A high-pressure physical property research technology for metal powders was established based on laser driving method. Through target optimization design and experimental verification, while achieving the regulation of shock wave loading characteristics, the technical difficulties caused by the lack of fixed geometric shapes in powder materials for measurement have been solved; The use of local coating method in the target structure solves the influence of adhesive on the thickness measurement of quartz standard material, ensuring the authenticity of the data. By utilizing three-dimensional CT imaging technology to characterize the assembly quality of experimental targets, micro targets that meet the requirements of laser driven metal powder high-pressure physical property diagnosis were obtained through improved assembly methods, and the development of targets with different initial densities was also achieved. The experimental results show good data consistency, which is consistent with the independently calculated WEOS simulation results and can effectively distinguish the data trends under different initial densities. This experimental technique can be extended to the study of high-pressure physical properties of other powder particles.